Se-NADA
Tocris Bioscience, part of Bio-Techne | Catalog # 7449
Key Product Details
| Description: | Orange fluorescent benzoselenadiazole D-amino acid (FDAA) for imaging bacteria; also photosensitizer |
| Chemical Name: | 3-((7-Nitro-2,1,3-benzoselenadiazol-4-yl)amino)-D-alanine hydrochloride |
| Purity: | ≥95% (HPLC) |
| Molecular Weight: | 366.62 |
Biological Activity for Se-NADA
Se-NADA is an orange fluorescent benzoselenadiazole D-amino acid (FDAA) for imaging bacteria. It is covalently incorporated into peptidoglycans in the cell walls of live bacteria. It also acts as a photosensitizer, bringing about bacterial cell death on exposure to visible light. Se-NADA is effective against both Gram-positive and Gram-negative bacteria. Ex/Em = 470/590 nm.
Licensing Information
Sold under license from the University of Edinburgh
Optical Data for Se-NADA
| Emission Color | Orange |
|---|---|
| λabs | 470 nm |
| λem | 590 nm |
| Cell Permeable | Yes |
| Application | Fluorescence Microscopy |
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Application of Se-NADA in B subtilis bacteria cells. Fluorescence microscopy image of B subtilis bacterial cells treated with SeNADA (250 μM, red) proving incorporation of the D-amino acid into the peptidoglycans of the cell wall. Image kindly provided by Dr Erkin Kuru, Department of Genetics, Harvard Medical School, Boston. |
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
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