Recombinant Porcine CCL2/MCP1 Protein

Name: Recombinant Porcine CCL2/MCP1 Protein
Brand: Novus Biologicals
SKU: NBP2-62499

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62499

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Product Specifications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

Pichia pastoris

Accession #

P42831

Conjugate

Unconjugated

Applications

ELISA, Western Blot

View all CCL2/MCP1 Proteins and Enzymes »

Product Specifications

Description

Recombinant pig MCP-1.

Source:Pichia pastoris

Amino Acid Sequence:aa 24 - 99 of porcine monocyte chemotactic protein 1 (MCP-1), UniProt P42831

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

8.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation and Storage

NBP2-62499

Preparation Method	Recombinant protein expressed in Pichia pastoris and purified by ion-exchange chromatography.
Formulation	PBS
Preservative	10% Trehalose
Concentration	Lyoph
Reconstitution	Reconstitute with 20 ul sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix vial after reconstitution.
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C. Avoid freeze-thaw cycles.

Background: CCL2/MCP1

Monocyte Chemoattracctant Protein-1 (MCP1), also known as CCL2, is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli and is a chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. MCP1 augments monocyte anti-tumor activity and has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. In atherosclerosis MCP-1 has been implicated to be involved in the recruitment of monocytes into the arterial wall during the disease process.

Alternate Names

C-C motif chemokine 2, chemokine (C-C motif) ligand 2, GDCF-2, HC11Monocyte secretory protein JE, MCAFMonocyte chemotactic and activating factor, MCP1 Monocyte chemotactic protein 1, MCP-1 Small-inducible cytokine A2, MGC9434, Monocyte chemoattractant protein 1, monocyte chemoattractant protein-1, SCYA2HSMCR30, small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je), small inducible cytokine subfamily A (Cys-Cys), member 2, SMC-CF

Gene Symbol

CCL2

UniProt

P42831 (Porcine)

Additional CCL2/MCP1 Products

Product Documents for Recombinant Porcine CCL2/MCP1 Protein

Product Datasheets

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COA

Product Specific Notices for Recombinant Porcine CCL2/MCP1 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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