Recombinant Rat CCL22/MDC Protein

Name: Recombinant Rat CCL22/MDC Protein
Brand: Novus Biologicals
SKU: NBP2-35269

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-35269

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Product Specifications
Scientific Data
Preparation & Storage
Background
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Specific Notices

Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

Bioactivity, SDS-PAGE

View all CCL22/MDC Proteins and Enzymes »

Product Specifications

Description

A single, non-glycosylated polypeptide chain containing 68 amino acids corresponding to CCL22/MDC Source: E. coli

Amino Acid Sequence: GPYGANVEDS ICCQDYIRHP LPPRFVKEFY WTSKSCRKPG VVLITIKNRD ICADPRMLWV KKILHKLA

Purity

>95%, by SDS-PAGE and HPLC

Endotoxin Level

Less than 1 EU/ug of CCL22/MDC as determined by LAL method.

Predicted Molecular Mass

7.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

MDC Protein is fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 10-100 ng/ml.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Rat CCL22/MDC Protein

SDS-PAGE: Recombinant Rat CCL22/MDC Protein [NBP2-35269]

SDS-Page: Rat CCL22/MDC Protein [NBP2-35269]

Formulation, Preparation and Storage

NBP2-35269

Formulation	Lyophilized from a 0.2 um filtered concentrated solution in 2 x PBS, pH7.4.
Preservative	No Preservative
Concentration	Lyoph
Reconstitution	Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL.
Format	Carrier-Free
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: CCL22/MDC

CCL22 is a protein encoded by the CCL22 gene. It is highly expressed in macrophage, monocyte-derived dendritic cell and thymus, additionally, also detected in the tissues of thymus, lymph node and appendix. CCL22 can bind to CCR4, and is a chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells, but not for neutrophils, eosinophils, and resting T-lymphocytes. After secreted from monocyte-derived dendritic cells, the protein can be proteolytic cleaved into three forms: MDC (3-69), MDC (5-69), MDC (7-69).

Alternate Names

ABCD-1, MDC, STCP-1, CCL22, MDC/CCL22

Gene Symbol

CCL22

Additional CCL22/MDC Products

Product Documents for Recombinant Rat CCL22/MDC Protein

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COA

Product Specific Notices for Recombinant Rat CCL22/MDC Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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