Recombinant Mouse CCL22/MDC Protein

Name: Recombinant Mouse CCL22/MDC Protein
Brand: Novus Biologicals
SKU: NBP2-35167

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-35167

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Product Specifications
Scientific Data
Preparation & Storage
Background
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Specific Notices

Key Product Details

Source

E. coli

Accession #

O88430

Conjugate

Unconjugated

Applications

SDS-PAGE

View all CCL22/MDC Proteins and Enzymes »

Product Specifications

Description

A single, non-glycosylated polypeptide chain containing 68 amino acids corresponding to CCL22/MDC Source: E. coli

Uniprot ID: O88430

Amino Acid Sequence: GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKLS

Purity

>97%, by SDS-PAGE

Endotoxin Level

Less than 1 EU/ug of CCL22/MDC as determined by LAL method.

Predicted Molecular Mass

7.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Mouse CCL22/MDC Protein

SDS-PAGE: Recombinant Mouse CCL22/MDC Protein [NBP2-35167]

SDS-Page: Mouse CCL22/MDC Protein [NBP2-35167]

Formulation, Preparation and Storage

NBP2-35167

Formulation	Lyophilized from a 0.2 um filtered concentrated solution in 2x PBS, 0.02% Tween-20, pH 7.0.
Preservative	5% Trehalose
Concentration	Lyoph
Reconstitution	Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at <-20C.
Format	Carrier-Free
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: CCL22/MDC

CCL22 is a protein that in mouse is encoded by the CCL22 gene, which locates on the Chr. 8. It is highly expressed in macrophage, monocyte-derived dendritic cell and thymus, additionally, also detected in the tissues of thymus, lymph node and appendix. CCL22 can bind to CCR4, and is a chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells, but not for neutrophils, eosinophils, and resting T-lymphocytes. After secreted from monocyte-derived dendritic cells, the protein can be proteolytic cleaved into three forms: MDC (3-69), MDC (5-69), MDC (7-69).

Alternate Names

ABCD-1, MDC, STCP-1, CCL22, MDC/CCL22

Gene Symbol

CCL22

UniProt