Recombinant Rat CCL7/MCP-3/MARC Protein

Name: Recombinant Rat CCL7/MCP-3/MARC Protein
Brand: Novus Biologicals
SKU: NBP2-35267

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-35267

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Product Specifications
Scientific Data
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Specific Notices

Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

Bioactivity, SDS-PAGE

View all CCL7/MCP-3/MARC Proteins and Enzymes »

Product Specifications

Description

A single non-glycosylated polypeptide chain containing 74 amino acids corresponding to CCL7/MCP-3/MARC Source: E. coli

Uniprot ID: Q9QXY8

Amino Acid Sequence: QPDGTNSSTC CYVKKQKIPK RNLKSYRKIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTS TPKP

Purity

>95%, by SDS-PAGE and HPLC

Endotoxin Level

Less than 1 EU/ug of CCL7/MCP-3/MARC as determined by LAL method.

Predicted Molecular Mass

8.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

MCP3 Protein is fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/ml.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Rat CCL7/MCP-3/MARC Protein

SDS-PAGE: Recombinant Rat CCL7/MCP-3/MARC Protein [NBP2-35267]

SDS-Page: Rat CCL7/MCP-3/MARC Protein [NBP2-35267]

Formulation, Preparation and Storage

NBP2-35267

Formulation	Lyophilized from a 0.2 um filtered concentrated solution in 2 x PBS, pH 7.4.
Preservative	No Preservative
Concentration	Lyoph
Reconstitution	Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at <-20C.
Format	Carrier-Free
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: CCL7/MCP-3/MARC

Rat CCL7, belonging to the CC chemokine family, is also named as MCP-3, because the sequence comparison suggested that the rat CCL7 is a homologue of the human MCP-3 and is postulated the rat MCP-3. The MCP-3 protein family signals through CCR2 expect MCP-1 and possess cross-reacts across species. CCL7/MCP3 has chemotactic functions for monocytes and eosinophils, but not for neutrophils. Additionally, it can activated NK cells as well as CD4+ and CD8+ T lymphocytes. CCL7 was found to interact with MMP2.

Alternate Names

MARC, MCP-3, CCL7, MCP-3/CCL7

Gene Symbol

CCL7

Additional CCL7/MCP-3/MARC Products

Product Documents for Recombinant Rat CCL7/MCP-3/MARC Protein

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COA

Product Specific Notices for Recombinant Rat CCL7/MCP-3/MARC Protein

This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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