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Recombinant Human CHMP1a His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22770

Novus Biologicals, part of Bio-Techne
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NBP2-22770

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-196 of Human CHMP1a

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDDTLFQ LKFTAKQLEK LAKKAEKDSK AEQAKVKKAL LQKNVECARV YAENAIRKKN EGVNWLRMAS RVDAVASKVQ TAVTMKGVTK NMAQVTKALD KALSTMDLQK VSSVMDRFEQ QVQNLDVHTS VMEDSMSSAT TLTTPQEQVD SLIMQIAEEN GLEVLDQLSQ LPEGASAVGE SSVRSQEDQL SRRLAALRN

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

24.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human CHMP1a His Protein

Recombinant Human CHMP1a His Protein SDS-Page: CHMP1a Protein [NBP2-22770]

SDS-Page: CHMP1a Protein [NBP2-22770]

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation and Storage

NBP2-22770
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.1 M NaCl, 20% glycerol, 1 mM DTT
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CHMP1a

Charged multivesicular body protein 1a, also known as CHMP1A, belongs to the vacuolar sorting protein family and functions as chromatin-modifying protein. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), as well as required for the formation of these bodies. The MVBs pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. CHMP1 interacts with VPS4B and localizes to early endosomes. Two isoforms, encoded by distinct genes, exists for CHMP1. They are designated CHMP1A and CHMP1B. Recombinant human CHMP1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

CHMP1, CHMP1charged multivesicular body protein 1/chromatin modifying protein 1, chromatin modifying protein 1A, Chromatin-modifying protein 1a, hVps46-1, KIAA0047charged multivesicular body protein 1a, PCOLN3protease, metallo, 1, 33kD, procollagen (type III) N-endopeptidase, PRSM1CHMP1a, Vacuolar protein sorting-associated protein 46-1, VPS46-1, Vps46A

Gene Symbol

CHMP1A

Additional CHMP1a Products

Product Documents for Recombinant Human CHMP1a His Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human CHMP1a His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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