DYRK1A Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76559PEP

Novus Biologicals, part of Bio-Techne
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NBP1-76559PEP
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Key Product Details

Source

Synthetic

Conjugate

Unconjugated

Applications

Antibody Competition

View all DYRK1A Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 17 amino acids near the carboxy terminus of human DYRK1A.

Source: Synthetic

(Accession #: NP_001387)

Purity

N/A

Application Notes

This peptide is useful as a blocking peptide for NBP1-76559.

For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NBP1-76559PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: DYRK1A

DYRK1A encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms.

Long Name

Dual-specificity Tyrosine-[Y]-phosphorylation Regulated Kinase 1A

Alternate Names

MNBH

Gene Symbol

DYRK1A

Additional DYRK1A Products

Product Documents for DYRK1A Antibody Blocking Peptide

Product Datasheets

Certificate of Analysis

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Product Specific Notices for DYRK1A Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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