Recombinant Human Follistatin Protein

Name: Recombinant Human Follistatin Protein
Brand: Novus Biologicals
SKU: NBP3-07105

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07105

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Product Specifications
Preparation & Storage
Background
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Key Product Details

Source

E. coli

Conjugate

Unconjugated

View all Follistatin Proteins and Enzymes »

Product Specifications

Description

A single non-glycosylated polypeptide chain containing 288 amino acids corresponding to Follistatin Source: E. coli

Amino Acid Sequence: GNCWLRQAKN GRCQVLYKTE LSKEECCSTG RLSTSWTEED VNDNTLFKWM IFNGGAPNCI PCKETCENVD CGPGKKCRMN KKNKPRCVCA PDCSNITWKG PVCGLDGKTY RNECALLKAR CKEQPELEVQ YQGRCKKTCR DVFCPGSSTC VVDQTNNAYC VTCNRICPEP ASSEQYLCGN DGVTYSSACH LRKATCLLGR SIGLAYEGKC IKAKSCEDIQ CTGGKKCLWD FKVGRGRCSL CDELCPDSKS DEPVCASDNA TYASECAMKE AACSSGVLLE VKHSGSCN

Purity

>95%, by SDS-PAGE and HPLC

Endotoxin Level

Less than 1 EU/ug of Follistatin as determined by LAL method.

Predicted Molecular Mass

31.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation and Storage

NBP3-07105

Formulation	Lyophilized from a 0.2 mm filtered concentrated solution in 20 mM Tris-HCl (pH 8.5), 150 mM NaCl.
Preservative	No Preservative
Concentration	Lyoph
Reconstitution	Briefly centrifuge vial prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at -20C.
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: Follistatin

FST, also known as Follistatin, has a 344 amino acid long isoform that is 38 kDa and a short 317 amino acid that is 35 kDa, functions as an activin antagonist binding directly to it and inhibits the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). Studies of this protein are being performed in relation to polycystic ovary syndrome, pituitary adenoma, insulin resistance, Down syndrome, plasmacytoma, lymphocytic leukemia, pituitary tumor infertility, endometrial carcinoma, teratocarcinoma, azoospermia, meningitis, hepatocellular carcinoma, ovarian carcinoma, liver disease, endometriosis, prostate carcinoma, prostatitis, ovarian cancer, and adenoma. This protein has been also shown to have interactions with ANG, DIP2A, BMP4, FN1, and TXN in signal transduction activin A signaling regulation and TGF-beta signaling pathways.

Alternate Names

FS, FST

Gene Symbol

FST

Additional Follistatin Products

Product Documents for Recombinant Human Follistatin Protein

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COA

Product Specific Notices for Recombinant Human Follistatin Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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