FXR/NR1H4 Antibody Blocking Peptide

Name: FXR/NR1H4 Antibody Blocking Peptide
Brand: Novus Biologicals
SKU: NB400-153PEP

Novus Biologicals, part of Bio-Techne | Catalog # NB400-153PEP

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Product Specifications
Preparation & Storage
Background
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Key Product Details

Conjugate

Unconjugated

Applications

Antibody Competition

View all FXR/NR1H4 Proteins and Enzymes »

Product Specifications

Description

A NR1H4 antibody blocking peptide.

Application Notes

This peptide is useful as a blocking peptide for NB400-153. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NB400-153 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NB400-153PEP

Formulation	Peptide dissolved in dH2O. Contains no BSA.
Preservative	No Preservative
Concentration	1.0 mg/ml
Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -80C. Avoid freeze-thaw cycles.

Background: FXR/NR1H4

FXR and LXR fall into a category of proteins termed orphan receptors; because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid. The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and bind DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, as well as several novel receptors including LXR (also referred to as RLD-1) and FXR.

Long Name

Farnesoid X-activated receptor

Alternate Names

BAR, HRR-1, NR1H4, RIP14

Gene Symbol

NR1H4

Additional FXR/NR1H4 Products

Product Documents for FXR/NR1H4 Antibody Blocking Peptide

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COA

Product Specific Notices for FXR/NR1H4 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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