Recombinant Human GilZ His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22895

Novus Biologicals, part of Bio-Techne
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NBP2-22895
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all GilZ Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-134 of Human GilZ

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMNTEMYQ TPMEVAVYQL HNFSISFFSS LLGGDVVSVK LDNSASGASV VAIDNKIEQA MDLVKNHLMY AVREEVEILK EQIRELVEKN SQLERENTLL KTLASPEQLE KFQSCLSPEE PAPESPQVPE APGGSAV

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

17.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human GilZ His Protein

SDS-PAGE: Recombinant Human GilZ His Protein [NBP2-22895]

SDS-PAGE: Recombinant Human GilZ His Protein [NBP2-22895]

SDS-Page: GilZ Protein [NBP2-22895]

Formulation, Preparation and Storage

NBP2-22895
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 10% glycerol, 1 mM DTT
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GilZ

TSC22 domain family protein 3, also known as TSC22D3, protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, TSC22D3 plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, TSC22D3 inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Recombinant human TSC22D3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

Delta sleep-inducing peptide immunoreactor, DSIP-immunoreactive leucine zipper protein, DSIP-immunoreactive peptide, GILZDKFZp313A1123, Glucocorticoid-induced leucine zipper protein, Protein DIP, TSC22 domain family protein 3, TSC22 domain family, member 3, TSC-22 related protein, TSC-22-like protein, TSC-22-related protein, TSC-22Rimmunoreactor

Gene Symbol

TSC22D3

Additional GilZ Products

Product Documents for Recombinant Human GilZ His Protein

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human GilZ His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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