GNG11 Recombinant Protein Antigen

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81811PEP

Novus Biologicals, part of Bio-Techne
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NBP1-81811PEP
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Key Product Details

Source

E. coli

Tag

N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

Conjugate

Unconjugated

Applications

Antibody Competition

View all GNG11 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human GNG11.

Source: E. coli

Amino Acid Sequence: EQLRKEVKLQRQQVSKCSEEIKNY

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

Purity

>80% by SDS-PAGE and Coomassie blue staining

Predicted Molecular Mass

21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications

Antibody Competition (10 - 100 molar excess)

Application Notes

This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP1-81811.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Protein / Peptide Type

Recombinant Protein Antigen

Formulation, Preparation and Storage

NBP1-81811PEP
Formulation PBS and 1M Urea, pH 7.4.
Preservative No Preservative
Concentration Please see the vial label for concentration. If unlisted please contact technical services.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: GNG11

GNG11, also known as Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11, is a 73 amino acid that is 8 kDa, plays a role in transmembrane signaling system, its beta and gamma chains are essential for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. This protein has been linked to splenic marginal zone lymphoma disease. The GNG11 protein has shown an interaction with ZHX1, GNB1, SMURF1, AMOTL2, GCG, and over 20 other proteins in several pathways including chemokine signaling pathway, glutamatergic synapse, cholinergic synapse, signal transduction cAMP signaling, G-protein signaling regulation of p38 and JNK signaling mediated by G-proteins, G-protein signaling G-Protein alpha-i signaling cascades, inhibitory action of lipoxins and resolvin E1 on neutrophil functions, signal transduction activation of PKC via G-Protein coupled receptor, molecular mechanisms of cancer, intracellular calcium signaling, CDK5 pathway, JNK pathway, and ERK5 signaling.

Alternate Names

GNGT11G protein gamma-11 subunit, guanine nucleotide binding protein (G protein), gamma 11, guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-11 subunit, guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11

Gene Symbol

GNG11

Additional GNG11 Products

Product Documents for GNG11 Recombinant Protein Antigen

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GNG11 Recombinant Protein Antigen

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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