Histone H2B, member S Antibody Blocking Peptide

Name: Histone H2B, member S Antibody Blocking Peptide
Brand: Novus Biologicals
SKU: NB100-56347PEP

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56347PEP

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Product Specifications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Conjugate

Unconjugated

Applications

Antibody Competition

View all Histone H2B, member S Proteins and Enzymes »

Product Specifications

Description

Application Notes

This peptide is useful as a blocking peptide for NB100-56347. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NB100-56347 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NB100-56347PEP

Formulation	Peptide dissolved in dH20. Contains no BSA.
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -80C. Avoid freeze-thaw cycles.

Background: Histone H2B, member S

Changes in chromatin structure play a large role in the regulation of transcription in eukaryotes (1). The nucleosome is the primary building block of chromatin, and is made up of four core histone proteins (H2A, H2B, H3 and H4) (2). Acetylation of core histones regulates gene expression (2). Histone H2B is primarily acetylated at lysines 5, 12, 15, and 20 (3). Ubiquitylation of Histone H2B at lysine 123 by Rad6 has been implicated in transcriptional activation and lysine methylation on histone H3 (4). Histone H2B phosphorylation at Ser10 (for yeast) and Ser14 (for mammalian cells) has been linked to regulation of apoptosis and meiosis (5).

Alternate Names

H2B histone family S member10H2B/s, H2B histone family, member S, Histone H2B.s

Gene Symbol

H2BFS

Additional Histone H2B, member S Products

Product Documents for Histone H2B, member S Antibody Blocking Peptide

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COA

Product Specific Notices for Histone H2B, member S Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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