Recombinant Human, Mouse IL-15 Fc, Mutant Protein [Biotin]

Name: Recombinant Human, Mouse IL-15 Fc, Mutant Protein [Biotin]
Brand: Novus Biologicals
SKU: NBP3-18179

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18179

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Product Datasheet / COA

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Product Specifications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

CHO

Conjugate

Biotin

Applications

SDS-PAGE

View all IL-15 Proteins and Enzymes »

Product Specifications

Description

Extracellular domain of human IL-15 (aa 49-162) including mutations at Q149D and Q156D fused to the N-terminus of the Fc region of mouse IgG2a.

Source: CHO cells

NCBI: NP_751914

Purity

>98%, by SDS-PAGE

Endotoxin Level

<0.06EU/ug protein (LAL test; Lonza).

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation and Storage

NBP3-18179

Formulation	Lyophilized from PBS
Preservative	0.09% Sodium Azide
Concentration	Lyoph
Reconstitution
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-15

IL-15 (14-15 kD) is a member of the four alpha-helical bundle family of cytokines. It is very similar to IL-2, except that IL-15 has an IL-15 alpha receptor subunit. IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules. This implies that IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases.

Long Name

Interleukin 15

Alternate Names

IL15

Gene Symbol