IL-15 Products
IL-15 (Interleukin 15) is a cytokine that induces or enhances the differentiation, maintenance, or activation of multiple T cell subsets including NK, NKT, Th17, Treg, and CD8+ memory cells. It also induces dendritic cell differentiation and inflammatory activation, exhibits anti-tumor activity, and inhibits the deposition of lipid in adipocytes. Complexes of IL-15 with cell surface IL-15 R alpha interact with complexes of IL-2 R beta and the Common gamma Chain on adjacent cells. This transpresentation mechanism enables cells to respond to IL-15 even if they do not express IL-15 R alpha. Ligation of membrane-associated IL-15/IL-15 R alpha complexes also induces reverse signaling that promotes activation of the IL-15/IL-15 R alpha expressing cells. The activity of circulating IL-15 is limited by its association with soluble IL-15 R alpha.
229 results for "IL-15" in Products
229 results for "IL-15" in Products
IL-15 Products
IL-15 (Interleukin 15) is a cytokine that induces or enhances the differentiation, maintenance, or activation of multiple T cell subsets including NK, NKT, Th17, Treg, and CD8+ memory cells. It also induces dendritic cell differentiation and inflammatory activation, exhibits anti-tumor activity, and inhibits the deposition of lipid in adipocytes. Complexes of IL-15 with cell surface IL-15 R alpha interact with complexes of IL-2 R beta and the Common gamma Chain on adjacent cells. This transpresentation mechanism enables cells to respond to IL-15 even if they do not express IL-15 R alpha. Ligation of membrane-associated IL-15/IL-15 R alpha complexes also induces reverse signaling that promotes activation of the IL-15/IL-15 R alpha expressing cells. The activity of circulating IL-15 is limited by its association with soluble IL-15 R alpha.
Analyzed by SEC-MALS
| Source: | E. coli |
| Accession #: | P40933.1 |
| Applications: | BA |
Intended for preclinical researchers who may transition to GMP IL-15 for their clinical work
| Source: | E. coli |
| Accession #: | P40933.1 |
| Applications: | BA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #IL15/7048R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #IL15/6971R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #IL15/7048R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #IL15/6971R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #IL15/7048R |
| Applications: | IHC |
| Sensitivity: | 2 pg/mL |
| Applications: | ELISA |
| Assay Range: | 3.9 - 250 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Source: | E. coli |
| Accession #: | P48346 |
| Applications: | BA |
Simple Plex Human IL-15 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #34559 |
| Applications: | ICFlow |
| Source: | E. coli |
| Accession #: | P40933.1 |
| Applications: | BA |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #34505 |
| Applications: | Neut |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #34559 |
| Applications: | WB, CyTOF-ready, ICFlow, Neut |
Simple Plex 32x4 panel containing IL-12 p70, IL-15, IL-18/IL-1F4, and IL-2 with sample diluent SD13. Part # starting with ST01 ships in 2-3 days. Sample type indicated with CS (cell culture).
| Applications: | Simple Plex |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #34593 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Dual ISH-IHC, Neut |
Simple Plex 32x2 panel containing IL-15 and IL-7 with sample diluent SD13. Part # starting with ST01 ships in 2-3 days. Sample type indicated with CS (Cell Culture Supernatant).
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #34559 |
| Applications: | ICFlow |
For use with catalog numbers D1500, S1500, PD1500
| Applications: | Ctrl |
Control for use with Human and Non-Human Primate IL-15 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
