Recombinant Human IL-17/IL-17A Protein
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-35040
Key Product Details
Product Specifications
Description
A disulfide-linked homodimer of two 132 amino acid polypeptide chains corresponding to IL-17/IL-17A Source: E. coli
Uniprot ID: Q16552
Amino Acid Sequence: GITIPRNPGC PNSEDKNFPR TVMVNLNIHN RNTNTNPKRS SDYYNRSTSP WNLHRNEDPE RYPSVIWEAK CRHLGCINAD GNVDYHMNSV PIQQEILVLR REPPHCPNSF RLEKILVSVG CTCVTPIVHH VA
Purity
>95%, by SDS-PAGE and HPLC
Endotoxin Level
Less than 1 EU/ug of IL-17/IL-17A as determined by LAL method.
Predicted Molecular Mass
31 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Activity
IL-17/IL-17A protein is fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 7.5 ng/ml, corresponding to a specific activity of > 1.3 x 105 IU/mg.
Protein / Peptide Type
Recombinant Protein
Scientific Data Images for Recombinant Human IL-17/IL-17A Protein
![SDS-PAGE: Recombinant Human IL-17/IL-17A Protein [NBP2-35040]](https://resources.bio-techne.com/images/products/Human-IL-17-IL-17A-Protein-SDS-Page-NBP2-35040-img0001.jpg "SDS-PAGE: Recombinant Human IL-17/IL-17A Protein [NBP2-35040]")
SDS-PAGE: Recombinant Human IL-17/IL-17A Protein [NBP2-35040]
SDS-Page: Human IL-17/IL-17A Protein [NBP2-35040]Formulation, Preparation and Storage
NBP2-35040
| Formulation | Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4. |
| Preservative | No Preservative |
| Concentration | Lyoph |
| Reconstitution | Recommended to centrifuge prior to opening. Reconstitute in 4 mM HCl to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at <-20C. |
| Format | Carrier-Free |
| Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles. |
Background: IL-17/IL-17A
Long Name
Interleukin 17
Alternate Names
CTLA-8, CTLA8, IL-17A, IL17, IL17A
Gene Symbol
IL17A
UniProt
Additional IL-17/IL-17A Products
Product Documents for Recombinant Human IL-17/IL-17A Protein
Product Specific Notices for Recombinant Human IL-17/IL-17A Protein
This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.
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