LDLR Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-06709PEP

Novus Biologicals, part of Bio-Techne
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NBP1-06709PEP
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Key Product Details

Conjugate

Unconjugated

Applications

Antibody Competition

View all LDLR Proteins and Enzymes »

Product Specifications

Description

A LDLR antibody blocking peptide.

Purity

Immunogen affinity purified

Application Notes

This peptide is useful as a blocking peptide for NBP1-06709. For further blocking peptide related protocol, click here. This peptide is useful as a negative control for Western blot.

Localization

Membrane; Single-pass type I membrane protein. Membrane ? clathrin-coated pit; Single-pass type I membrane protein.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NBP1-06709PEP
Formulation PBS, 30% glycerol
Preservative 0.1% Sodium Azide
Concentration 1.0 mg/ml
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: LDLR

The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor-mediated endocytosis (1). Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits (2). It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) was shown to be mediated by LDL receptors on cultured cells (3).

Long Name

Low Density Lipoprotein Receptor

Alternate Names

LDL R

Gene Symbol

LDLR

Additional LDLR Products

Product Documents for LDLR Antibody Blocking Peptide

Product Datasheets

Certificate of Analysis

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Product Specific Notices for LDLR Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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