Niemann-Pick C1 Antibody Blocking Peptide

Name: Niemann-Pick C1 Antibody Blocking Peptide
Brand: Novus Biologicals
SKU: NB400-148PEP

Novus Biologicals, part of Bio-Techne | Catalog # NB400-148PEP

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Technical Data
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Product Specifications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Conjugate

Unconjugated

Applications

Antibody Competition

View all Niemann-Pick Type C1/NPC1 Proteins and Enzymes »

Product Specifications

Description

A NPC1 antibody blocking peptide.

Application Notes

This peptide is useful as a blocking peptide for NB400-148. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NB400-148 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NB400-148PEP

Formulation	Peptide dissolved in dH2O. Contains no BSA.
Preservative	No Preservative
Concentration	1.0 mg/ml
Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -80C. Avoid freeze-thaw cycles.

Background: Niemann-Pick Type C1/NPC1

Niemann-Pick type C1 (NPC1) is a member of a family of genes encoding membrane-bound proteins containing putative sterol sensing domains. The protein regulates cholesterol transport from late endosomes-lysosomes to other intracellular compartments. NPC1 overexpression increases both the rate of trafficking of low density lipoprotein cholesterol to the endoplasmic reticulum and the rate of delivery of endosomal cholesterol to the plasma membrane. NPC disease is an inherited neurovisceral lipid storage disorder of unesterified cholesterol accumulation in lysosomes. It is characterized by progressive neural and liver degeneration, resulting from inactivating mutations in NPC1, in most cases.

Alternate Names

NPC1, SLC65A1

Gene Symbol

NPC1

Additional Niemann-Pick Type C1/NPC1 Products

Product Documents for Niemann-Pick C1 Antibody Blocking Peptide

Product Datasheets

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COA

Product Specific Notices for Niemann-Pick C1 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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