Recombinant Human PEA-15 Protein

Name: Recombinant Human PEA-15 Protein
Brand: Novus Biologicals
SKU: NBP1-30247

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-30247

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Technical Data
Citations & Reviews

Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

SDS-PAGE

View all PEA-15 Proteins and Enzymes »

Product Specifications

Description

An un-tagged recombinant protein corresponding to the amino acids 1-130 of Human PEA-15

Source: E.coli

Amino Acid Sequence: MAEYGTLLQD LTNNITLEDL EQLKSACKED IPSEKSEEIT TGSAWFSFLE SHNKLDKDNL SYIEHIFEIS RRPDLLTMVV DYRTRVLKIS EEDELDTKLT RIPSAKKYKD IIRQPSEEEI IKLAPPPKKA

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

15 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PEA-15 Protein

SDS-PAGE: Recombinant Human PEA-15 Protein [NBP1-30247]

SDS-Page: PEA15 Protein [NBP1-30247] - PEA-15, 15 kDa (130aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE

Formulation, Preparation and Storage

NBP1-30247

Formulation	20 mM Tris-HCl buffer (pH 7.5), 1 mM DTT, 10% glycerol
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PEA-15

Phospho-enriched protein in astrocytes 15 kDa (PEA-15) is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes. This protein has been implicated in the regulation of multiple cellular processes including apoptosis, proliferation, glucose transport, adhesion and migration. Increased PEA-15 levels may affect tumorigenesis and cancer progression, thus it is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. Recombinant human PEA-15 was expressed in E.coli and purified by using conventional chromatography.

Long Name

Phosphoprotein Enriched in Astrocytes 15

Alternate Names

HMAT1, HUMMAT1H, MAT1H, PEA15, PED

Gene Symbol

PEA15

Additional PEA-15 Products

Product Documents for Recombinant Human PEA-15 Protein

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COA

Product Specific Notices for Recombinant Human PEA-15 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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