Recombinant Human Persephin Protein

Name: Recombinant Human Persephin Protein
Brand: Novus Biologicals
SKU: NBP2-35208

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-35208

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Product Datasheet / COA

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Accession #

P06734

Conjugate

Unconjugated

Applications

Bioactivity, SDS-PAGE

View all Persephin Proteins and Enzymes »

Product Specifications

Description

A disulfide-linked homodimer of two 96 amino acid polypeptide chains corresponding to Persephin Source: E. coli

Uniprot ID: P06734

Amino Acid Sequence: ALSGPCQLWS LTLSVAELGL GYASEEKVIF RYCAGSCPRG ARTQHGLALA RLQGQGRAHG GPCCRPTRYT DVAFLDDRHR WQRLPQLSAA ACGCGG

Purity

> 97 % pure by SDS-PAGE and HPLC

Endotoxin Level

Less than 0.1 EU/ug of Persephin as determined by LAL method.

Predicted Molecular Mass

20.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

Persephin Protein is fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TT medullary thyroid cancer cells is less than 10 ng/ml, corresponding to a specific activity of > 1.0 x 10^5 IU/mg.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Persephin Protein

SDS-PAGE: Recombinant Human Persephin Protein [NBP2-35208]

SDS-Page: Recombinant Human Persephin Protein [NBP2-35208]

Formulation, Preparation and Storage

NBP2-35208

Formulation	Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Preservative	No Preservative
Concentration	Lyoph
Reconstitution	Recommended to centrifuge prior to opening. Reconstitute in 4 mM HCl to a concentration of 0.1-1.0mg/mL.
Format	Carrier-Free
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: Persephin

Persephin belongs to the GDNF ligand subfamily of the TGF-beta superfamily. It promotes the survival and growth of central dopaminergic and motor neurons, and also is involved in kidney development. But persephin does not support survival of peripheral neurons.

Alternate Names

PSPN

Gene Symbol