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Recombinant Human PP1 Inhibitor-2 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-23380

Novus Biologicals, part of Bio-Techne
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NBP2-23380

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-166 of Human PP1 Inhibitor-2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAASTAS HRPIKGILKN KTSTTSSMVA SAEQPRGNVD EELSKKSQKW DEMNILATYH PADKDYGLMK IDEPSTPYHS MMGDDEDACS DTEATEAMAP DILARKLAAA EGLEPKYRIQ EQESSGEEDS DLSPEEREKK RQFEMKRKLH YNEGLNIKLA RQLISKDLH

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PP1 Inhibitor-2 His Protein

SDS-PAGE: Recombinant Human PP1 Inhibitor-2 His Protein [NBP2-23380]

SDS-PAGE: Recombinant Human PP1 Inhibitor-2 His Protein [NBP2-23380]

SDS-Page: Recombinant Human PP1 Inhibitor-2 Protein [NBP2-23380]

Formulation, Preparation and Storage

NBP2-23380
Formulation 20 mM Tris-HCl buffer (pH8.0), 30% glycerol, 0.15 M NaCl, 1 mM DTT
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PP1 Inhibitor-2

PPP1R2 is an inhibitor of protein-phosphatase 1 and forms heterodimer with PP1. Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex. Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex. Recombinant human PPP1R2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

Protein Phosphatase 1 Inhibitor 2

Alternate Names

IPP2, PP1 Inhibitor2, PPP1R2

Gene Symbol

PPP1R2

Additional PP1 Inhibitor-2 Products

Product Documents for Recombinant Human PP1 Inhibitor-2 His Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human PP1 Inhibitor-2 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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