PP1 Inhibitor-2 Products
Protein Phosphatase 1 Inhibitor-2 (PP1 Inhibitor-2), also called PP1 regulatory subunit 2 (PP1R2), I2, and IPP2, binds to PP1 through an RVxF consensus sequence. The complex inactivates PP1, preventing it from dephosphorylating substrates such as glycogen phosphorylase. Unlike PP1 Inhibitor-1, the binding of PP1 Inhibitor-2 is Protein Kinase A phosphorylation-independent. Dissociation of the PP1 Inhibitor-2 complex is enhanced by phosphorylation at T72 by GSK-3, ERK, or CDK. Overexpression of PP1 Inhibitor-2 in mouse heart improves cardiac function without changing organ size.
11 results for "PP1 Inhibitor-2" in Products
11 results for "PP1 Inhibitor-2" in Products
PP1 Inhibitor-2 Products
Protein Phosphatase 1 Inhibitor-2 (PP1 Inhibitor-2), also called PP1 regulatory subunit 2 (PP1R2), I2, and IPP2, binds to PP1 through an RVxF consensus sequence. The complex inactivates PP1, preventing it from dephosphorylating substrates such as glycogen phosphorylase. Unlike PP1 Inhibitor-1, the binding of PP1 Inhibitor-2 is Protein Kinase A phosphorylation-independent. Dissociation of the PP1 Inhibitor-2 complex is enhanced by phosphorylation at T72 by GSK-3, ERK, or CDK. Overexpression of PP1 Inhibitor-2 in mouse heart improves cardiac function without changing organ size.
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #488123 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2E9 |
| Applications: | IHC, WB, ELISA |
![Immunohistochemistry-Paraffin: PP1 Inhibitor-2 Antibody (2E9) [H00005504-M01]](https://resources.bio-techne.com/images/products/PP1-Inhibitor-2-Antibody-2E9-Immunohistochemistry-Paraffin-H00005504-M01-img0004.jpg "Immunohistochemistry-Paraffin: PP1 Inhibitor-2 Antibody (2E9) [H00005504-M01]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: PP1 Inhibitor-2 Antibody [NBP2-56881]](https://resources.bio-techne.com/images/products/PP1-Inhibitor-2-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-56881-img0002.jpg "Immunocytochemistry/ Immunofluorescence: PP1 Inhibitor-2 Antibody [NBP2-56881]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PP1 Inhibitor-2 Antibody [NBP1-79889]](https://resources.bio-techne.com/images/products/PP1-Inhibitor-2-Antibody-Western-Blot-NBP1-79889-img0002.jpg "Western Blot: PP1 Inhibitor-2 Antibody [NBP1-79889]")
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human PP1 Inhibitor-2 His Protein [NBP2-23380]](https://resources.bio-techne.com/images/products/PPP1R2P3-Protein-SDS-Page-NBP2-23380-img0001.jpg "SDS-PAGE: Recombinant Human PP1 Inhibitor-2 His Protein [NBP2-23380]")
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: PP1 Inhibitor-2 Antibody [NBP2-48801]](https://resources.bio-techne.com/images/products/PP1-Inhibitor-2-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-48801-img0003.jpg "Immunocytochemistry/ Immunofluorescence: PP1 Inhibitor-2 Antibody [NBP2-48801]")
| Applications: | WB |
![Western Blot: PP1 Inhibitor-2 Overexpression Lysate [NBL1-14682]](https://resources.bio-techne.com/images/products/Protein-phosphatase-1-inhibitor-subunit-2-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-14682-img0002.jpg "Western Blot: PP1 Inhibitor-2 Overexpression Lysate [NBL1-14682]")
| Applications: | AC |
| Applications: | AC |