Recombinant Cynomolgus Monkey CD4 Fc Chimera Protein, CF
R&D Systems, part of Bio-Techne | Catalog # 11145-CD
Key Product Details
Source
CHO
Accession #
Structure / Form
Disulfide-linked homodimer
Conjugate
Unconjugated
Applications
Bioactivity
Product Specifications
Source
Chinese Hamster Ovary cell line, CHO-derived cynomolgus monkey CD4 protein
Cynomolgus Monkey CD4 (Lys26-Pro396) Accession # P79185.1 |
IEGRMD | Human IgG1 (Pro100-Lys330) |
N-terminus | C-terminus |
Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
N-terminal Sequence Analysis
Lys26
Predicted Molecular Mass
69 kDa
SDS-PAGE
80-88 kDa, under reducing conditions.
Activity
Measured by its binding ability in a functional ELISA with Human
CD4 Biotinylated Antibody
(Catalog #
BAF379). The ED50 for this
effect is 35.0-280 ng/mL.
Scientific Data Images for Recombinant Cynomolgus Monkey CD4 Fc Chimera Protein, CF
Recombinant Cynomolgus Monkey CD4 Fc Chimera Protein Binding Activity.
Measured by its binding ability in a functional ELISA with Human CD4 Biotinylated Antibody (BAF379). The ED50 for this effect is 35.0-280 ng/mL.Recombinant Cynomolgus Monkey CD4 Fc Chimera Protein SDS-PAGE.
2 μg/lane of Recombinant Cynomolgus Monkey CD4 Fc Chimera Protein (Catalog # 11145-CD) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing bands at 80-88 kDa and 160-180 kDa, respectively.Formulation, Preparation and Storage
11145-CD
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
Reconstitution | Reconstitute at 500 μg/mL in PBS. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Background: CD4
References
- Vignali, D.A.A. (2010) J. Immunol. 184:5933.
- Maddon, P.J. et al. (1985) Cell 42:93.
- Alarcon, B. and H.M. van Santen (2010) Sci. Signal. 3:pe11.
- Wan, Y.Y. and R.A. Flavell (2009) Mol. Cell Biol. 1:20.
- Kitchen, S.G. et al. (2005) Proc. Natl. Acad. Sci. 102:3794.
- Crocker, P.R. et al. (1987) J. Exp. Med. 166:613.
- Biswas, P. et al. (2003) Blood 101:4452.
- Bernstein, H.B. et al. (2006) J. Immunol. 177:3669.
- Funke, I. et al. (1987) J. Exp. Med. 165:1230.
- Doyle, C. and J.L. Strominger (1987) Nature 330:256.
- Huppa, J.B. et al. (2010) Nature 463:963.
- Fragoso, R. et al. (2003) J. Immunol. 170:913.
- Cruikshank, W.W. et al. (1994) Proc. Natl. Acad. Sci. 91:5109.
- Klatzmann, D. et al. (1984) Nature 312:767.
- Dagleish, A.G. et al. (1984) Nature 312:763.
Alternate Names
CD4
Entrez Gene IDs
Gene Symbol
CD4
UniProt
Additional CD4 Products
Product Documents for Recombinant Cynomolgus Monkey CD4 Fc Chimera Protein, CF
Product Specific Notices for Recombinant Cynomolgus Monkey CD4 Fc Chimera Protein, CF
For research use only
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