Recombinant Human Mcl-1 Western Blot Standard Protein

R&D Systems, part of Bio-Techne | Catalog # WBC003

R&D Systems, part of Bio-Techne
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WBC003
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Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

Western Blot

View all Mcl-1 Proteins and Enzymes »

Formulation, Preparation and Storage

WBC003
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Mcl-1

Mcl-1 (Myeloid Cell Leukemia 1) is a member of the Bcl-2 family of proteins. Alternative splicing results in two distinct isoforms: Mcl-1L (long) enhances cell survival by inhibiting apoptosis, while Mcl-1S (short) promotes apoptosis. The elimination of Mcl-1L is an early and required step for DNA damage-induced apoptosis. Degradation of Mcl-1L is regulated by polyubiquitination, which targets Mcl-1L to the proteasome pathway.

Long Name

Myeloid Cell Leukemia Sequence 1

Alternate Names

BCL2L3, Mcl1

Entrez Gene IDs

4170 (Human); 17210 (Mouse)

Gene Symbol

MCL1

Additional Mcl-1 Products

Product Documents for Recombinant Human Mcl-1 Western Blot Standard Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human Mcl-1 Western Blot Standard Protein

For research use only

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