Recombinant Mouse IGSF4C/SynCAM4 Fc Chimera Protein, CF
R&D Systems, part of Bio-Techne | Catalog # 9906-S4
Key Product Details
Source
NS0
Accession #
Structure / Form
Disulfide-linked homodimer
Conjugate
Unconjugated
Applications
Bioactivity
Product Specifications
Source
Mouse myeloma cell line, NS0-derived mouse IGSF4C/SynCAM4 protein
Mouse IGSF4C (Gln25-Ala324) Accession # Q8R464 |
IEGRMD | Human IgG1 (Pro100-Lys330) |
N-terminus | C-terminus |
Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
N-terminal Sequence Analysis
No results obtained. Gln25 inferred from enzymatic pyroglutamate treatment revealing Glu26.
Predicted Molecular Mass
60 kDa
SDS-PAGE
81-93 kDa, reducing conditions
Activity
Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons.
Recombinant Mouse IGSF4C/SynCAM4 Fc Chimera, immobilized at 0.5-1 μg/mL on a 96-well plate, is able to significantly enhance neurite outgrowth.
Recombinant Mouse IGSF4C/SynCAM4 Fc Chimera, immobilized at 0.5-1 μg/mL on a 96-well plate, is able to significantly enhance neurite outgrowth.
Scientific Data Images for Recombinant Mouse IGSF4C/SynCAM4 Fc Chimera Protein, CF
Recombinant Mouse IGSF4C/SynCAM4 Fc Chimera Protein Bioactivity
Recombinant Mouse IGSF4C/SynCAM4 Fc Chimera (Catalog # 9906-S4) Induces Cortical Neurite Outgrowth. A) Untreated E16-18 embryonic rat cortical neurons. B) Neurite outgrowth in E16-18 embryonic rat cortical neurons treated with 0.5 μg/mL of Recombinant Mouse IGSF4C/SynCAM4 Fc Chimera.Recombinant Mouse IGSF4C/SynCAM4 Fc Chimera Protein SDS-PAGE
2 μg/lane of Recombinant Mouse IGSF4C was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing bands at 81-93 kDa and 160-190 kDa, respectively.Formulation, Preparation and Storage
9906-S4
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution |
Reconstitute at 1 mg/mL in PBS.
|
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage |
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Background: IGSF4C/SynCAM4
References
- Fukuhara, H. et al. (2001) Oncogene 20:5401.
- Biederer, T. et al. (2006) Genomics 87:139.
- Takai, Y. et al. (2008) Nat. Rev. Mol. Cell Biol. 9:603.
- Thomas, L. A. et al. (2008) J. Comp. Neurol. 510:47.
- Williams, Y. N. et al. (2005) Oncogene 25:1446.
- Maurel, P. et al. (2007) J. Cell Biol. 178:861.
- Fogel, A. I. et al. (2007) J. Neurosci. 27:12516.
- Spiegel, I. et al. (2007) Nat. Neurosci. 10:861.
Long Name
Immunoglobulin Superfamily, Member 4B
Alternate Names
CADM4, Necl-4, SynCAM4, TSLC1-like 2, TSLL2
Gene Symbol
CADM4
UniProt
Additional IGSF4C/SynCAM4 Products
Product Documents for Recombinant Mouse IGSF4C/SynCAM4 Fc Chimera Protein, CF
Product Specific Notices for Recombinant Mouse IGSF4C/SynCAM4 Fc Chimera Protein, CF
For research use only
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