Recombinant Human SH2D1A His Protein

Name: Recombinant Human SH2D1A His Protein
Brand: Novus Biologicals
SKU: NBP1-50869

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-50869

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Technical Data
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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all SH2D1A Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-128 of Human SH2D1A

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MDAVAVYHGK ISRETGEKLL LATGLDGSYL LRDSESVPGV YCLCVLYHGY IYTYRVSQTE TGSWSAETAP GVHKRYFRKI KNLISAFQKP DQGIVIPLQY PVEKKSSARS TQGTTGIRED PDVCLKAP

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

16.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human SH2D1A His Protein

SDS-PAGE: Recombinant Human SH2D1A His Protein [NBP1-50869]

SDS-Page: Recombinant Human SH2D1A His Protein [NBP1-50869] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation and Storage

NBP1-50869

Formulation	PBS (pH 7.4)
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SH2D1A

SH2D1A is an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. This protein is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD) also known as Duncan disease. XLPD is characterized by a rare congenital immunodeficiency following Epstein-Barr virus (EBV) infection. Recombinant human SH2D1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Alternate Names

DSHP, EBVS, IMD5, LYP, MTCP1, XLP, XLPD

Gene Symbol

SH2D1A

Additional SH2D1A Products

Product Documents for Recombinant Human SH2D1A His Protein

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COA

Product Specific Notices for Recombinant Human SH2D1A His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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