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Recombinant Human Skp1 Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-30173

Novus Biologicals, part of Bio-Techne
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NBP1-30173
NBP1-30173-500ug

Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

SDS-PAGE

Product Specifications

Description

An un-tagged recombinant protein corresponding to the amino acids 1- 160 of Human Skp1

Source: E.coli

Amino Acid Sequence: MPSIKLQSSD GEIFEVDVEI AKQSVTIKTM LEDLGMDDEG DDDPVPLPNV NAAILKKVIQ WCTHHKDDPP PPEDDENKEK RTDDIPVWDQ EFLKVDQGTL FELILAANYL DIKGLLDVTC KTVANMIKGK TPEEIRKTFN IKNDFTEEEE AQVGSTQFCL

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

18 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Skp1 Protein

SDS-PAGE: Recombinant Human Skp1 Protein [NBP1-30173]

SDS-PAGE: Recombinant Human Skp1 Protein [NBP1-30173]

SDS-Page: Recombinant Human Skp1 Protein [NBP1-30173] - 15% SDS-Page (3ug)

Formulation, Preparation and Storage

NBP1-30173
Formulation 20 mM Tris-HCl buffer (pH8.0), 50 mM NaCl, 10% glycerol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SKP1

S-phase kinase-associated protein 1, also known as SKP1, is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to proteins containing an F-box motif, such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis. It is also involved in the control of beta-catenin levels and the activity of beta-catenin dependent TCF transcription factors. Recombinant human SKP1 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

S-phase Kinase Associated Protein 1

Alternate Names

OCP2, p19a, p19Skp1, SKP1A

Gene Symbol

SKP1

Additional SKP1 Products

Product Documents for Recombinant Human Skp1 Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human Skp1 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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