SUCNR1/GPR91 Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-00861PEP

Novus Biologicals, part of Bio-Techne
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NBP1-00861PEP
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Key Product Details

Conjugate

Unconjugated

Applications

Antibody Competition

View all SUCNR1/GPR91 Proteins and Enzymes »

Product Specifications

Description

Application Notes

This peptide is useful as a blocking peptide for NBP1-00861. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NBP1-00861 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NBP1-00861PEP
Formulation Peptide dissolved in dH20. Contains no BSA.
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: SUCNR1/GPR91

GPR91 (formerly known as P2U2) is a G protein-coupled, dicarboxylic acid succinate receptor. It has a high level of expression in the kidney, predominantly in the proximal tubules, and localizes to the plasma membrane. It has also been found at low levels in the liver and the spleen. GPR91 functions as a citric acid cycle intermediate succinate receptor. Two signaling pathways result from GPR91 activation, the pertussis-toxin-sensitive Gi/Go pathway and the pertussis-toxin-insensitive Gq pathway. Four amino acid residues are necessary for GPR91 activation by succinate: Arg 99, His 103, Arg 252 and Arg 281. GPR91 plays an important role in the succinate-induced hypertensive effect and may be involved in renovascular hypertension, a disease linked to diabetes, renal failure and atherosclerosis.

Long Name

Succinate Receptor 1

Alternate Names

GPR91

Gene Symbol

SUCNR1

Additional SUCNR1/GPR91 Products

Product Documents for SUCNR1/GPR91 Antibody Blocking Peptide

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SUCNR1/GPR91 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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