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Recombinant Human TACI/TNFRSF13B/CVID Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61308

Novus Biologicals, part of Bio-Techne
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NBP2-61308-1000ug
NBP2-61308-100ug
NBP2-61308-500ug
NBP2-61308-5ug

Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

Bioactivity, Western Blot

Product Specifications

Description

A single non-glycosylated polypeptide chain containing 160 amino acids corresponding to TACI/TNFRSF13B/CVID Source: E. coli

Uniprot ID: O14836

Amino Acid Sequence: MSGLGRSRRG GRSRVDQEER FPQGLWTGVA MRSCPEEQYW DPLLGTCMSC KTICNHQSQR TCAAFCRSLS CRKEQGKFYD HLLRDCISCA SICGQHPKQC AYFCENKLRS PVNLPPELRR QRSGEVENNS DNSGRYQGLE HRGSEASPAL PGLKLSADQV

Purity

>95%, by SDS-PAGE and HPLC

Endotoxin Level

Less than 1 EU/ug of TACI/TNFRSF13B/CVID as determined by LAL method.

Predicted Molecular Mass

18 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

Fully biologically active when compared to standard. The biological activity is determined by its ability to block human BAFF induced T2B cell survival using a concentration range of 1.0-3.0 ug/ml.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human TACI/TNFRSF13B/CVID Protein

SDS-PAGE: Recombinant Human TACI/TNFRSF13B/CVID Protein [NBP2-61308]

SDS-PAGE: Recombinant Human TACI/TNFRSF13B/CVID Protein [NBP2-61308]

SDS-Page: Recombinant Human TACI/TNFRSF13B/CVID Protein [NBP2-61308]

Formulation, Preparation and Storage

NBP2-61308
Formulation Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Preservative No Preservative
Concentration Lyoph
Reconstitution Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at <-20C.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: TACI/TNFRSF13B

TACI is a lymphocyte specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein binds to both APRIL and BAFF and induces activation of the transcription factors NFAT (nuclear-factor of activated T cells), AP1, and NF kappa B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith Magenis syndrome region on chromosome 17.

Long Name

Transmembrane Activator and CAML Interactor/Tumor Necrosis Factor Receptor Superfamily Member 13B

Alternate Names

CD267, CVID, TNFRSF13B

Gene Symbol

TNFRSF13B

Additional TACI/TNFRSF13B Products

Product Documents for Recombinant Human TACI/TNFRSF13B/CVID Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human TACI/TNFRSF13B/CVID Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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