Simple Plex Control for Human Amyloid Beta aa1-42

Name: Simple Plex Control for Human Amyloid Beta aa1-42
Brand: ProteinSimple
SKU: 897078

ProteinSimple, part of Bio-Techne | Catalog # 897078

Product Datasheet / COA

Control for use with Human Amyloid Beta aa1-42 Simple Plex Assay Cartridge Kit

Summary for Simple Plex Control for Human Amyloid Beta aa1-42

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of Human Amyloid Beta aa1-42 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Amyloid Precursor Protein (APP) is a type I transmembrane protein that is ubiquitously expressed on cell surfaces. It undergoes complex proteolytic processing and is cleaved by alpha-, beta-, and gamma-Secretases to generate soluble APP alpha, soluble APP beta, and Amyloid beta (A beta) fragments of several lengths. One of these fragments, A beta 42, generated by beta- and gamma-Secretase activities, has been implicated in Alzheimer's disease. Aberrantly high levels of this peptide form and accumulate in the brains of Alzheimer's disease patients to create the senile plaques characteristic of the disease.

Product Specifications for Simple Plex Control for Human Amyloid Beta aa1-42

Species	Human
Applications	Simple Plex Automated Immunoassay
Source	N/A

Preparation & Storage

Shipping Conditions

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: Amyloid beta

Item	Value
Entrez Gene IDs	351 (Human); 11820 (Mouse)
Alternate Names	Abeta, Amyloid beta, beta-Amyloid Peptide

Product Documents for Simple Plex Control for Human Amyloid Beta aa1-42

Product Datasheets

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