Summary for Simple Plex Control for Human CCL20/MIP-3 alpha
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human CCL20/MIP-3 alpha concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
CCL20, also known as MIP-3 alpha, is a chemokine that plays an important role in dendritic cell trafficking and recruitment and activation of T cells. It is upregulated in monocytes, T cells, endothelial cells, epithelial cells, and fibroblasts following inflammatory stimulation. CCL20 signals through CCR6 which is expressed on memory T cells, B cells and bone marrow-derived dendritic cells.
Product Specifications for Simple Plex Control for Human CCL20/MIP-3 alpha
Species
Human
Applications
Control, Simple Plex Automated Immunoassay
Source
N/A
Preparation & Storage
Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt. • Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended. • Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: CCL20/MIP-3 alpha
Item
Value
Entrez Gene IDs
6364 (Human); 20297 (Mouse); 29538 (Rat)
Alternate Names
Beta-chemokine exodus-1, C-C motif chemokine 20, CC chemokine LARC, CCL20, CKb4, LARC, LARCLiver and activation-regulated chemokine, MIP-3 alpha, MIP-3-alpha, MIP-3a, MIP3 alpha, MIP3AMacrophage inflammatory protein 3 alpha, SCYA20Small-inducible cytokine A20, ST38, beta chemokine exodus-1, chemokine (C-C motif) ligand 20, exodus-1, small inducible cytokine subfamily A (Cys-Cys), member 20
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