Simple Plex Control for Human VEGF-C

Name: Simple Plex Control for Human VEGF-C
Brand: ProteinSimple
SKU: 898231

ProteinSimple, part of Bio-Techne | Catalog # 898231

Product Datasheet / COA

Control for use with Human VEGF-C Simple Plex Cartridge Kit

Key Product Details

Technical Data
Citations

Summary for Simple Plex Control for Human VEGF-C

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human VEGF-C concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Vascular endothelial growth factor C (VEGF-C) is a homodimeric ligand of VEGF R3/Flt-4 and is synthesized with N- and C-terminal propeptides. Fully processed VEGF-C containing only the VEGF homology domain can additionally bind and activate VEGF R2/KDR/Flk-1. VEGF-C interactions with VEGF R3 are critical for lymphangiogenesis. Both the ligand and receptor are usually co-expressed at sites of lymphatic vessel sprouting, in the embryo, and in various pathological conditions. Over-expression of VEGF-C in tumor cells induces tumoral lymphatic hyperplasia, neoangiogenesis, and vessel sprouting, resulting in enhanced lymph flow and metastasis to regional lymph nodes.

Product Specifications for Simple Plex Control for Human VEGF-C

Species	Human
Applications	Control, Simple Plex Automated Immunoassay
Source	N/A

Preparation & Storage

Shipping Conditions

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: VEGF-C

Item	Value
Long Name	Vascular Endothelial Growth Factor C
Entrez Gene IDs	7424 (Human); 22341 (Mouse)
Alternate Names	Flt4 ligand, Flt4-L, VEGF-C, VEGFC, VRPFLT4 ligand DHM, Vascular endothelial growth factor-related protein, vascular endothelial growth factor C

Product Documents for Simple Plex Control for Human VEGF-C

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