SARS-CoV2 Multi-Antigen Serology Module

Simple Western SARS-CoV-2 serology assay demonstrates differential patient reactivity to N, S1 RBD, S1 full length, S2 full length, and Spike (S1+S2) COVID-19 viral antigens

Simple Western SARS-CoV-2 serology assay demonstrates differential human serum reactivity to N, S1 RBD, S1 full length, S2 full length, and Spike (S1+S2) COVID-19 viral antigens. Quantification of percent peak area for SARS-CoV-2 antigens detected by PCR positive human serum.

Simple Western SARS-CoV-2 serology assay is validated for human serum and plasma. Differential patient reactivity of PCR positive human plasma samples to N, S1 RBD, S1 full length, S2 full length, and Spike (S1+S2) COVID-19 viral antigens

Workflow schematic of the Simple Western SARS-CoV-2 serology assay.

Faster time to data with exceptional sensitivity! The SARS-CoV-2 Multi-Antigen Serology Module for Simple Western™ provides an immune fingerprint of serum antibodies against five antigens commonly associated with SARS-CoV-2 infection in only three hours. As little as 1 µL of serum can be utilized for each patient sample. Titer studies have shown sensitivity down to 1:138,240 with R2 linearity >0.99 across the dilution series. Download the app note to learn more about a serial dilution study that demonstrates both assay linearity and unparalleled sensitivity to SARS-CoV-2 antigens.

Linearity of SARS-CoV-2 Antibodies in Human Serum Serial dilution study demonstrating assay sensitivity and linearity. Dilution series run from 1:40 to 1:138240. Not visible in the electropherogram are 1:17280, 1:34560, 1:69120, and 1:138240