A 68930 hydrochloride

Name: A 68930 hydrochloride
Brand: Tocris Bioscience
SKU: 1534

Tocris Bioscience, part of Bio-Techne | Catalog # 1534

Citations (6)

COA / SDS

Potent and selective D1-like agonist

Key Product Details

Description:	Potent and selective D₁-like agonist
Chemical Name:	cis-(±)-1-(Aminomethyl)-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	307.78

View Full Technical Details for A 68930 hydrochloride

Technical Data
Citations

Biological Activity for A 68930 hydrochloride

A 68930 hydrochloride is a potent and selective D₁-like dopamine receptor agonist (EC₅₀ values are 2.1 and 3910 nM for D₁-like and D₂-like receptors respectively). Centrally active following systemic administration in vivo.

Technical Data for A 68930 hydrochloride

M. Wt	307.78
Formula	C₁₆H₁₇NO₃.HCl
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	130465-39-3
PubChem ID	9904672
InChi Key	PQPGUUQPTSMLKU-YYLIZZNMSA-N
Smiles	OC1=C(O)C=CC2=C1C[C@@H]([C@]3=CC=CC=C3)O[C@H]2CN.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for A 68930 hydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	15.39	50

Preparing Stock Solutions for A 68930 hydrochloride

The following data is based on the product molecular weight 307.78.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	6.50 mL	32.49 mL	64.98 mL
2.5 mM	1.30 mL	6.50 mL	13.00 mL
5 mM	0.65 mL	3.25 mL	6.50 mL
25 mM	0.13 mL	0.65 mL	1.30 mL

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References for A 68930 hydrochloride

References are publications that support the biological activity of the product.

Kebabian A68930: a potent and specific agonist for the D-1 DA receptor. Am.J.Hypertens. 1990 PMID: 2143387
Quaglia (1R,3S)-1-(Aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran: a potent and selective D1 agonist. J.Med.Chem. 1990 PMID: 1977907
Deveney and Waddingto Psychopharmacological distinction between novel full-efficacy "D1-like" DA receptor agonists. Pharmacol.Biochem.Behav. 1997 PMID: 9300618