A-71623

Tocris Bioscience, part of Bio-Techne | Catalog # 2411

COA / SDS

Potent and selective CCK1 agonist; suppresses feeding

Key Product Details

Purity:	≥95%
Molecular Weight:	840.97 kDa

View Full Technical Details for A-71623

Technical Data
Citations

Biological Activity for A-71623

A-71623 is a potent CCK₁ agonist (IC₅₀ = 3.7 nM) with 1200-fold selectivity over the CCK₂ receptor. Suppresses food intake following central or peripheral administration.

Technical Data for A-71623

M. Wt	840.97 kDa
Formula	C₄₄H₅₆N₈O₉
Storage	Store at -20°C
Purity	≥95%
CAS Number	130408-77-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for A-71623

Solubility

Soluble Soluble to 1 mg/ml in 20mM PBS buffer

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References for A-71623

References are publications that support the biological activity of the product.

Asin et al. A-71623, a selective CCK-A receptor agonist, suppresses food intake in the mouse, dog, and monkey. Pharmacol.Biochem.Behav., 1992;42:699 PMID: 1513850
DeNinno et al. Development of CCK-tetrapeptide analogues as potent and selective CCK-A receptor agonists. J.Med.Chem., 1990;33:2951
Lin et al. Characterization of two novel cholecystokinin tetrapeptide (30-33) analogues, A-71623 and A-70874, that exhibit high potency and selectivity for cholecystokinin-A receptors. Mol.Pharmacol., 1990;39:346