AC 55649

Name: AC 55649
Brand: Tocris Bioscience
SKU: 2436

Tocris Bioscience, part of Bio-Techne | Catalog # 2436

COA / SDS

Selective RARβ2 agonist

Discontinued Product

2436 has been discontinued. View all Retinoic Acid Receptor Agonists products.

Key Product Details

Description:	Selective RARβ2 agonist
Chemical Name:	4'-Octyl-[1,1'-biphenyl]-4-carboxylic acid
Purity:	≥99% (HPLC)
Molecular Weight:	310.44

View Full Technical Details for AC 55649

Technical Data
Citations

Biological Activity for AC 55649

AC 55649 is a potent, isoform-selective RARβ2 receptor agonist (pEC₅₀ values are 6.9, 5.7 and 5.6 at RARβ2, RARβ1 and RARα respectively) that displays 100-fold selectivity versus other retinoid receptors. Inhibits proliferation of the breast cancer cell line MCF-7.

Technical Data for AC 55649

M. Wt	310.44
Formula	C₂₁H₂₆O₂
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	59662-49-6
PubChem ID	1714884
InChi Key	HXBKPYIEQLLNBK-UHFFFAOYSA-N
Smiles	CCCCCCCCC1=CC=C(C=C1)C1=CC=C(C=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for AC 55649

References are publications that support the biological activity of the product.

Lund Design, synthesis, and structure-activity analysis of isoform selective retinoic acid receptor ligands. J.Med.Chem. 2009 PMID: 19239230
Lund Discovery of a potent, orally available, and isoform-selective retinoic acid β2 receptor agonist. J.Med.Chem. 2005 PMID: 16302793

AC 55649

Tocris Bioscience, part of Bio-Techne | Catalog # 2436

Key Product Details

Biological Activity for AC 55649

Technical Data for AC 55649

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for AC 55649

Product Documents for AC 55649

COA

Certificate of Analysis

SDS

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