Amyloid β-peptide (25-35) (human)

Name: Amyloid β-peptide (25-35) (human)
Brand: Tocris Bioscience
SKU: 1429

Tocris Bioscience, part of Bio-Techne | Catalog # 1429

COA / SDS

Human amyloid β-protein fragment functionally required for neurotoxicity

Key Product Details

Description:	Human amyloid β-protein fragment functionally required for neurotoxicity
Purity:	≥95% (HPLC)
Molecular Weight:	1060.27

View Full Technical Details for Amyloid β-peptide (25-35) (human)

Technical Data
Citations

Biological Activity for Amyloid β-peptide (25-35) (human)

Amyloid β-peptide (25-35) (human) is a fragment of human amyloid β-peptide, functionally required for the neurotrophic and neurotoxic effects associated with Alzheimer's disease.

Technical Data for Amyloid β-peptide (25-35) (human)

M. Wt	1060.27
Formula	C₄₅H₈₁N₁₃O₁₄S
Single Letter Sequence	GSNKGAIIGLM
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	131602-53-4
PubChem ID	10843733
InChi Key	WIHBNMPFWRHGDF-SLVFWPMISA-N
Smiles	[H]NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Amyloid β-peptide (25-35) (human)

Solubility

Soluble to 0.5mg/ml in water

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References for Amyloid β-peptide (25-35) (human)

References are publications that support the biological activity of the product.

Schenk Therapeutic approaches related to amyloid-β peptide and Alzheimer's Disease J.Med.Chem. 1995 PMID: 7473539
Yankner Neurotrophic and neurotoxic effects of amyoid β protein: reversal by tachykinin neuropeptides. Science 1990 PMID: 2218531
Rush Intracerebral β-amyloid(25-35) produces tissue damage: is it neurotoxic? Neurobiol.Aging 1992 PMID: 1281289