Anandamide

Biological Activity for Anandamide

Technical Data for Anandamide

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Anandamide

References for Anandamide

References are publications that support the biological activity of the product.

• Costa M, Fonseca B, Teixeira N, Correia-da-Silva G The endocannabinoid anandamide induces apoptosis in cytotrophoblast cells: involvement of both mitochondrial and death receptor pathways. Placenta, 2014;36(1):69-76. 2014 PMID: 25465706
• Wilhelmsen K, Khakpour S, Tran A, Sheehan K, Schumacher M, Xu F, Hellman J The endocannabinoid/endovanilloid N-arachidonoyl dopamine (NADA) and synthetic cannabinoid WIN55,212-2 abate the inflammatory activation of human endothelial cells. J Biol Chem, 2014;289(19):13079-100. 2014 PMID: 24644287
• Kaczocha M, Rebecchi M, Ralph B, Teng Y, Berger W, Galbavy W, Elmes M, Glaser S, Wang L, Rizzo R, Deutsch D, Ojima I Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. PLoS ONE, 2014;9(4):e94200. 2014 PMID: 24705380
• Pertwee Pharmacology of cannabinoid receptor ligands. Curr.Med.Chem., 1999;6:635 PMID: 10469884
• Ryberg et al. The orphan receptor GPR55 is a novel cannabinoid receptor. Br.J.Pharmacol., 2007;152:1092 PMID: 17876302
• Devane et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science, 1992;258:1946 PMID: 1470919
• Sancho et al. Anandamide inhibits nuclear factor-κB activation through a cannabinoid receptor-independent pathway. Mol.Pharmacol., 2003;63:429 PMID: 12527815
• Ross et al. Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens. Br.J.Pharmacol., 2001;132:631 PMID: 11159715
• Ellermann et al. Endocannabinoids inhibit the induction of virulence in enteric pathogens. Cell, 2020; PMID: 33031742