β-Funaltrexamine hydrochloride

Name: β-Funaltrexamine hydrochloride
Brand: Tocris Bioscience
SKU: 0926

Tocris Bioscience, part of Bio-Techne | Catalog # 0926

Citations (4)

COA / SDS

Irreversible and selective μ antagonist

Discontinued Product

0926 has been discontinued. View all mu Opioid Receptor Antagonists products.

Key Product Details

Description:	Irreversible and selective μ antagonist
Alternative Names:	β-FNA
Chemical Name:	(E)-4-[[5α,6β)-17-Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]amino]-4-oxo-2-butenoicacid methyl ester hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	490.99

View Full Technical Details for β-Funaltrexamine hydrochloride

Technical Data
Citations

Biological Activity for β-Funaltrexamine hydrochloride

β-Funaltrexamine hydrochloride is a selective μ opioid receptor antagonist.

Licensing Information

Sold with the permission of the University of Minnesota

Technical Data for β-Funaltrexamine hydrochloride

M. Wt	490.99
Formula	C₂₅H₃₀N₂O₆.HCl
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	72786-10-8
PubChem ID	44522395
InChi Key	BIPHUOBUKMPSQR-NQGXHZAGSA-N
Smiles	Cl.[H][C@@]12OC3=C4C(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)\C=C\C(=O)OC)=CC=C3O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for β-Funaltrexamine hydrochloride

References are publications that support the biological activity of the product.

Takemorei The irreversible narcotic antagonist and reversible agonist properties of the fumarate methyl ester derivative of naltr. Eur.J.Pharmacol. 1981 PMID: 6263637
Jiang μ Antagonist and κ agonist properties of β-funaltrexamine (β-FNA) in vivo: long lasting spinal analgesia in mice. J.Pharmacol.Exp.Ther. 1990 PMID: 2156986