BD 1047 dihydrobromide

Name: BD 1047 dihydrobromide
Brand: Tocris Bioscience
SKU: 0956

Tocris Bioscience, part of Bio-Techne | Catalog # 0956

(1)

Citations (16)

COA / SDS

σ1 selective antagonist

Key Product Details

Chemical Name:	N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine dihydrobromide
Purity:	≥99%
Molecular Weight:	437.04 kDa

View Full Technical Details for BD 1047 dihydrobromide

Technical Data
Citations / Reviews (1)

Biological Activity for BD 1047 dihydrobromide

BD 1047 dihydrobromide is a σ₁ receptor antagonist, exhibiting a similar binding profile to that of BD 1063 (Cat. No. 0883) but with higher affinity (approximately 10-fold) at both σ₁ and σ₂ sites.

Technical Data for BD 1047 dihydrobromide

M. Wt	437.04 kDa
Formula	C₁₃H₂₀Cl₂N₂.2HBr
Storage	Desiccate at +4°C
Purity	≥99%
CAS Number	138356-21-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for BD 1047 dihydrobromide

Solubility

Soluble Soluble to 50 mM in water and to 50 mM in DMSO

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References for BD 1047 dihydrobromide

References are publications that support the biological activity of the product.

Romieu et al. Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference. Neuroreport, 2000;11:2885 PMID: 11006959
Matsumoto et al. Characterisation of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism. Eur.J.Pharmacol., 1995;280:301 PMID: 8566098
Garrone et al. Effects of traz. on neurotransmitter release from rat mossy fibre cerebellar synaptosomes. Eur.J.Pharmacol., 2000;400:35 PMID: 10913582