BDNF (human)

Name: BDNF (human)
Brand: Tocris Bioscience
SKU: 2837
Rating: 5 (2 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 2837

(2)

Citations (8)

COA / SDS

Activates TrkB and p75 receptors

Key Product Details

Description:	Activates TrkB and p75 receptors
Purity:	≥95% (HPLC)
Molecular Weight:	26984

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Technical Data
Citations / Reviews (2)

Biological Activity for BDNF (human)

BDNF (human) is a member of the neurotrophin growth factor family that binds and activates TrkB and p75 neurotrophin receptors. BDNF enhances the survival, growth and differentiation of neurons. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease. In an animal model of Huntington's disease, BDNF administration or overexpression rescues the disease phenotype.

Technical Data for BDNF (human)

M. Wt	26984
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	218441-99-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for BDNF (human)

References are publications that support the biological activity of the product.

Zuccato Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery. Pharmacol.Res. 2005 PMID: 15967378
Evans and Barker Neurotrophic factors as a therapeutic target for Parkinson's disease. Expert Opin.Ther.Targets 2008 PMID: 18348680
Wang The when and where of BDNF and the antidepressant response. Biol.Psychiat. 2008 PMID: 18329441
Lipsky and Marini Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity. Ann.N.Y.Acad.Sci. 2007 PMID: 18077569

BDNF (human)

Tocris Bioscience, part of Bio-Techne | Catalog # 2837

Key Product Details

Biological Activity for BDNF (human)

Technical Data for BDNF (human)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for BDNF (human)

Product Documents for BDNF (human)

COA

Certificate of Analysis

SDS

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