Budesonide

Name: Budesonide
Brand: Tocris Bioscience
SKU: 2671

Tocris Bioscience, part of Bio-Techne | Catalog # 2671

Citations (11)

COA / SDS

Synthetic glucocorticoid; anti-inflammatory and chemopreventive

Key Product Details

Chemical Name:	(11β,16α)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione
Purity:	≥98%
Molecular Weight:	430.53 kDa

View Full Technical Details for Budesonide

Technical Data
Citations

Biological Activity for Budesonide

Budesonide is a synthetic anti-inflammatory glucocorticoid that displays chemopreventive activity. Prevents formation of lung adenomas and adenocarcinomas in mice following inhalation or oral administration. Reverses DNA hypomethylation and modulates expression of cancer related genes.

Technical Data for Budesonide

M. Wt	430.53 kDa
Formula	C₂₅H₃₄O₆
Storage	Store at RT
Purity	≥98%
CAS Number	51333-22-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Budesonide

Solubility

Soluble Soluble to 100 mM in DMSO and to 50 mM in ethanol

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References for Budesonide

References are publications that support the biological activity of the product.

Burke S, Goff M, Updegraff B, Lu D, Brown P, Minkin S, Biggerstaff J, Zhao L, Karlstad M, Collier J Regulation of the CCL2 Gene in Pancreatic beta-Cells by IL-1beta and Glucocorticoids: Role of MKP-1. PLoS ONE, 2012;7(10):e46986. 2012 PMID: 23056550
Spencer et al. Budesonide. A review of its pharmacological properties and therapeutic efficacy in inflammatory bowel disease. Drugs, 1995;50:854 PMID: 8586030