CG 428-Neg

Name: CG 428-Neg
Brand: Tocris Bioscience
SKU: 7426

Tocris Bioscience, part of Bio-Techne | Catalog # 7426

COA / SDS

Negative control for CG 428 (Cat. No. 7425)

Key Product Details

Description:	Negative control for CG 428 (Cat. No. 7425)
Chemical Name:	2-(1-Methyl-2,6-dioxo-3-piperidinyl)-4-[[2-[3-[4-[6-[6-[(2R)-2-(3-fluorophenyl)-1-pyrrolidinyl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-1-piperazinyl]-3-oxopropoxy]ethyl]amino]-1H-isoindole-1,3(2H)-dione
Purity:	≥98% (HPLC)
Molecular Weight:	828.91

View Full Technical Details for CG 428-Neg

Technical Data
Citations

Biological Activity for CG 428-Neg

Negative control for CG 428 (Cat. No. 7425).

Licensing Information

Sold under license from Cullgen

Technical Data for CG 428-Neg

M. Wt	828.91
Formula	C₄₄H₄₅FN₁₀O₆
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	2714560-39-9
InChi Key	INNUOJBTOZECFW-BONSOQDYSA-N
Smiles	FC1=CC=CC([C@H]2CCCN2C3=NN4C(C=C3)=NC=C4C5=NC(N6CCN(C(CCOCCNC7=C8C(N(C(C8=CC=C7)=O)C9CCC(N(C)C9=O)=O)=O)=O)CC6)=CC=C5)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for CG 428-Neg

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	82.89	100

Preparing Stock Solutions for CG 428-Neg

The following data is based on the product molecular weight 828.91.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.21 mL	6.03 mL	12.06 mL
5 mM	0.24 mL	1.21 mL	2.41 mL
10 mM	0.12 mL	0.60 mL	1.21 mL
50 mM	0.02 mL	0.12 mL	0.24 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for CG 428-Neg

References are publications that support the biological activity of the product.

Chen Discovery of first-in-class potent and selective tropomyosin receptor kinase degraders. J.Med.Chem. 2020 PMID: 33058680