ci-IP3/PM

Name: ci-IP3/PM
Brand: Tocris Bioscience
SKU: 6210

Tocris Bioscience, part of Bio-Techne | Catalog # 6210

Citations (21)

COA / SDS

Caged inositol triphosphate

Key Product Details

Description:	Caged inositol triphosphate
Chemical Name:	6-O-[(4,5-Dimethoxy-2-nitrophenyl)methyl]-2,3-O-(1-methylethylidene)-D-myo-Inositol 1,4,5-tris[bis[(1-oxopropoxy)methyl]phosphate]
Purity:	≥98% (HPLC)
Molecular Weight:	1171.87

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Technical Data
Citations

Biological Activity for ci-IP3/PM

ci-IP3/PM is a caged inositol triphosphate. Cell permeable. UV photolysis (λ = 330 nm) in HeLa cells releases i-IP₃, promoting Ca²⁺-release from internal stores.

F 127 (Cat. No. 6253) for the solubilization of ci-IP3/PM is also available.

Technical Data for ci-IP3/PM

M. Wt	1171.87
Formula	C₄₂H₆₄NO₃₁P₃
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1009832-82-9
PubChem ID	124221754
InChi Key	FNWIHZJMPHUCAI-RJQNPCEJSA-N
Smiles	CC(O1)(C)O[C@H]([C@H]1[C@@H](OP(OCOC(CC)=O)(OCOC(CC)=O)=O)[C@@H]2OP(OCOC(CC)=O)(OCOC(CC)=O)=O)[C@@H](OP(OCOC(CC)=O)(OCOC(CC)=O)=O)[C@@H]2OCC3=CC(OC)=C(OC)C=C3[N+]([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for ci-IP3/PM

References are publications that support the biological activity of the product.

Lock Comparison of Ca²⁺ puffs evoked by extracellular agonists and photoreleased IP₃. Cell Calcium 2017 PMID: 28108028
Zhang Endothelin-1 and IP₃ induced Ca²⁺ sparks in pulmonary arterial smooth muscle cells. J.Cardiovasc.Pharmacol. 2004 PMID: 15838259
Dakin and Li Cell membrane permeable esters of D-myo-inositol 1,4,5-trisphosphate. Cell Calcium 2007 PMID: 17307252

ci-IP3/PM

Tocris Bioscience, part of Bio-Techne | Catalog # 6210

Key Product Details

Biological Activity for ci-IP3/PM

Technical Data for ci-IP3/PM

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for ci-IP3/PM

Product Documents for ci-IP3/PM

COA

Certificate of Analysis

SDS

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