CS 2100

Tocris Bioscience, part of Bio-Techne | Catalog # 4543

COA / SDS

Selective S1P1 agonist

Key Product Details

Chemical Name:	1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid
Purity:	≥97%

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Technical Data
Citations

Biological Activity for CS 2100

CS 2100 is a sphingosine-1-phosphate receptor 1 (S1P₁) agonist (EC₅₀ = 4.0 nM). Exhibits 5000-fold selectivity for human S1P₁ over S1P₃. Displays efficacy in a rat adjuvant-induced arthritis model.

Technical Data for CS 2100

Formula	C₂₅H₂₃N₃O₄S
Storage	Store at +4°C
Purity	≥97%
CAS Number	913827-99-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for CS 2100

Solubility

Soluble Soluble to 5 mM in DMSO with gentle warming

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References for CS 2100

References are publications that support the biological activity of the product.

Nakamura et al. Synthesis and evaluation of CS-2100, a potent, orally active and S1P₃-sparing S1P₁ agonist. Eur.J.Med.Chem., 2012;51:92 PMID: 22405291
Nakamura et al. Discovery of CS-2100, a potent, orally active and S1P₃-sparing S1P₁ agonist. Bioorg.Med.Chem.Lett., 2012;22:1788 PMID: 22264485

CS 2100

Tocris Bioscience, part of Bio-Techne | Catalog # 4543

Key Product Details

Biological Activity for CS 2100

Technical Data for CS 2100

Solubility for CS 2100

Dilution Calculator

Reconstitution Calculator

References for CS 2100

Product Documents for CS 2100

COA

Certificate of Analysis

SDS

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