CYM 5520

Name: CYM 5520
Brand: Tocris Bioscience
SKU: 5418

Tocris Bioscience, part of Bio-Techne | Catalog # 5418

COA / SDS

Selective S1P2 allosteric agonist

Key Product Details

Description:	Selective S1P₂ allosteric agonist
Chemical Name:	1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-1,6-dihydro-6-oxo-3-pyridinecarbonitrile
Purity:	≥99% (HPLC)
Molecular Weight:	345.39

View Full Technical Details for CYM 5520

Technical Data
Citations

Biological Activity for CYM 5520

CYM 5520 is a selective S1P₂ allosteric agonist (EC₅₀ = 0.48 μM). Selective for S1P₂ receptors over a panel of 29 other receptors and transporters.

Technical Data for CYM 5520

M. Wt	345.39
Formula	C₂₁H₁₉N₃O₂
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	1449747-00-5
PubChem ID	25110470
InChi Key	FMYGNANMYYHBSU-UHFFFAOYSA-N
Smiles	CC1=C(C(CN3C=C(C#N)C=CC3=O)=O)C=C(C)N1CC2=CC=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for CYM 5520

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	34.54	100

Preparing Stock Solutions for CYM 5520

The following data is based on the product molecular weight 345.39.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.90 mL	14.48 mL	28.95 mL
5 mM	0.58 mL	2.90 mL	5.79 mL
10 mM	0.29 mL	1.45 mL	2.90 mL
50 mM	0.06 mL	0.29 mL	0.58 mL

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Reconstitution Calculator

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References for CYM 5520

References are publications that support the biological activity of the product.

Satsu A sphingosine 1-phosphate receptor 2 selective allosteric agonist. Bioorg.Med.Chem. 2013 PMID: 23849205