CyPPA

Name: CyPPA
Brand: Tocris Bioscience
SKU: 2953

Tocris Bioscience, part of Bio-Techne | Catalog # 2953

(1)

Citations (20)

COA / SDS

KCa2.2 and KCa2.3 (SK) channel activator

Key Product Details

Chemical Name:	N-Cyclohexyl-N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-4-pyrimidinamine
Purity:	≥99%

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Technical Data
Citations / Reviews (1)

Biological Activity for CyPPA

CyPPA is an activator of small conductance Ca²⁺-activated K⁺ channels that displays selectivity for K_Ca2.2 (SK2) and K_Ca2.3 (SK3) channels (EC₅₀ values are 5.6 and 14 μM for K_Ca2.3 and K_Ca2.2 respectively). Displays no activity at K_Ca2.1 (SK1) and K_Ca3.1 (IK) channels.

Technical Data for CyPPA

Formula	C₁₆H₂₃N₅
Storage	Store at +4°C
Purity	≥99%
CAS Number	73029-73-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for CyPPA

References are publications that support the biological activity of the product.

Hougaard et al. Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca²⁺-activated K⁺ channels. Br.J.Pharmacol., 2007;151:655 PMID: 17486140

CyPPA

Tocris Bioscience, part of Bio-Techne | Catalog # 2953

Key Product Details

Biological Activity for CyPPA

Technical Data for CyPPA

Dilution Calculator

Reconstitution Calculator

References for CyPPA

Product Documents for CyPPA

COA

Certificate of Analysis

SDS

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