(D)-PPA 1

Name: (D)-PPA 1
Brand: Tocris Bioscience
SKU: 6515

Tocris Bioscience, part of Bio-Techne | Catalog # 6515

Citations (1)

COA / SDS

PD-1/PD-L1 interaction inhibitor

Key Product Details

Purity:

≥95%

View Full Technical Details for (D)-PPA 1

Technical Data
Citations

Biological Activity for (D)-PPA 1

(D)-PPA 1 is a PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (K_d = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo.

Technical Data for (D)-PPA 1

Formula	C₇₀H₉₈N₂₀O₂₁
Storage	Store at -20°C
Purity	≥95%
CAS Number	1620813-53-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for (D)-PPA 1

Solubility

Soluble Soluble to 2 mg/ml in water

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References for (D)-PPA 1

References are publications that support the biological activity of the product.

Chang et al. Blocking of the PD-1/PD-L1 interaction by a D-peptide antagonist for cancer immunotherapy. Angew Chem.Int.Ed.Engl., 2015;54:11760 PMID: 26259671

(D)-PPA 1

Tocris Bioscience, part of Bio-Techne | Catalog # 6515

Key Product Details

Biological Activity for (D)-PPA 1

Technical Data for (D)-PPA 1

Solubility for (D)-PPA 1

Dilution Calculator

Reconstitution Calculator

References for (D)-PPA 1

Product Documents for (D)-PPA 1

COA

Certificate of Analysis

SDS

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