(±)-Cloprostenol sodium salt

Name: (±)-Cloprostenol sodium salt
Brand: Tocris Bioscience
SKU: 2295

Tocris Bioscience, part of Bio-Techne | Catalog # 2295

COA / SDS

Water-soluble PGF2α analog and potent FP receptor agonist

Discontinued Product

2295 has been discontinued. View all Prostanoid Receptor Agonists products.

Key Product Details

Description:	Water-soluble PGF₂_α analog and potent FP receptor agonist
Chemical Name:	(5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid monosodium salt
Purity:	≥98% (HPLC)
Molecular Weight:	446.9

View Full Technical Details for (±)-Cloprostenol sodium salt

Technical Data
Citations

Biological Activity for (±)-Cloprostenol sodium salt

(±)-Cloprostenol sodium salt is a water-soluble prostaglandin F_2α (PGF_2α) analog; acts as a potent FP receptor agonist (EC₅₀ = 0.84 nM). Potently inhibits differentiation of adipocyte precursor cells. Luteolytic agent in vivo.

Technical Data for (±)-Cloprostenol sodium salt

M. Wt	446.9
Formula	C₂₂H₂₈ClNaO₆
Storage	Desiccate at -20°C
Purity	≥98% (HPLC)
CAS Number	55028-72-3
PubChem ID	17756794
InChi Key	IFEJLMHZNQJGQU-KXXGZHCCSA-M
Smiles	[Na+].O[C@@H](COC1=CC(Cl)=CC=C1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for (±)-Cloprostenol sodium salt

References are publications that support the biological activity of the product.

Griffin Pharmacological characterization of an FP prostaglandin receptor on rat vascular smooth muscle cells (A7r5) coupled to phosphoinositide turnover and intracellular calcium mobilization. J.Pharmacol.Exp.Ther. 1998 PMID: 9655886
Serrero and Lepak Prostaglandin F_2α receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined medium. Biochem.Biophys.Res.Comm.
Dukes Potent luteolytic agents related to prostaglandin F_2α. Nature 1974 PMID: 4853720

(±)-Cloprostenol sodium salt

Tocris Bioscience, part of Bio-Techne | Catalog # 2295

Key Product Details

Biological Activity for (±)-Cloprostenol sodium salt

Technical Data for (±)-Cloprostenol sodium salt

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for (±)-Cloprostenol sodium salt

Product Documents for (±)-Cloprostenol sodium salt

COA

Certificate of Analysis

SDS

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