E 64d

Biological Activity for E 64d

Technical Data for E 64d

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for E 64d

References for E 64d

References are publications that support the biological activity of the product.

• Kim et al. Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer. Autophagy, 2008;4:659 PMID: 18424912
• Sato et al. Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res., 2007;67:9677 PMID: 17942897
• Tanada et al. Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. Autophagy, 2005;1:84 PMID: 16874052
• Wilcox and Mason Inhibition of cysteine proteinases in lysosomes and whole cells. Biochem.J., 1992;285:495 PMID: 1637341
• Hoffmann et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically-proven protease inhibitor. Cell, 2020; PMID: 32142651