EC 23

Name: EC 23
Brand: Tocris Bioscience
SKU: 4011

Tocris Bioscience, part of Bio-Techne | Catalog # 4011

Citations (26)

COA / SDS

Synthetic retinoid; induces differentiation of stem cells

Key Product Details

Chemical Name:	4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoic acid
Purity:	≥99%
Molecular Weight:	332.44 kDa

View Full Technical Details for EC 23

Technical Data
Citations

Biological Activity for EC 23

EC 23 is a photostable synthetic retinoid; analog of ATRA (Cat. No. 0695). Displays similar activity to ATRA when tested on the embryonal carcinoma stem cell model TERA2.cl.SP12. Potently induces neural differentiation in human pluripotent embryonic stem cells.

Technical Data for EC 23

M. Wt	332.44 kDa
Formula	C₂₃H₂₄O₂
Storage	Store at +4°C
Purity	≥99%
CAS Number	104561-41-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for EC 23

Solubility

Soluble Soluble to 100 mM in DMSO and to 5 mM in ethanol

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References for EC 23

References are publications that support the biological activity of the product.

Christie et al. Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation. Org.Biomol.Chem., 2008;6:3497 PMID: 19082150
Barnard et al. Synthetic retinoids: structure-activity relationships. Chemistry, 2009;15:11430 PMID: 19821467
Maltman et al. Proteomic profiling of the stem cell response to retinoic acid and synthetic retinoid analogues: identification of major retinoid-inducible proteins. Mol.Biosyst., 2009;5:458 PMID: 19381361